DIM inhibits an enzyme called aromatase, which converts testosterone to estrogen.
DIM activates the enzyme that converts E1 and E2 to the "good" estrogen: E3. Estrogen dominance was linked to abdominal fat gain, common in post-menopausal women.
Taking DIM supplements as part of a healthy diet was found to help with abdominal fat loss. Do DIM capsules help with "bad" estrogen ?ĭIM capsules support the activity of enzymes that improve estrogen metabolism by increasing the levels of 2-hydroxyestrone, e.g., the "good" estrogen. This leads to acne breakouts and a dull complexion. This androgen-dependent secretion of sebum is regulated by testosterone and the more potent dihydrotestosterone (DHEA). As more androgens (testosterone) bind to the sebaceous glands' receptors, more sebum is produced. What is the effect of excess androgens on acne?Īndrogens represent the skin's most important sebum-producing hormones in both males and females. These imbalance symptoms include mood swings, decreased sex drive, worsening PMS, bloating, weight gain, anxiety, irregular or heavy menstrual periods, and hair loss. The body produces less progesterone for women with estrogen dominance but keeps producing the same estrogen levels, causing a hormonal imbalance. What is estrogen dominance ?Įstrogen dominance happens when the body produces too much estrogen. E3, on the other hand, is regarded as a "good" estrogen and may protect against cancer. It's considered the "bad" estrogen and may be the source of estrogen's cancer-causing properties. In menopause, E1 becomes the primary estrogen.
E2 is the most common form of estrogen in non-pregnant females from puberty to menopause. There are three types of estrogens : estrone (E1), estradiol (E2), and estriol (E3). Wait, what do you mean by "bad" estrogen ? Like spironolactone, it is believed the DIM binds to the androgen receptor and reduces its effects on the skin's oil glands. It does this by adjusting the activity of metabolic enzymes and estrogen receptors, reducing the amount of "bad" estrogen in the body. Instead, DIM works to balance the body's natural response to estrogen and testosterone. The DIM is one of the most popular natural supplements for women with hormonal imbalance and hormonal breakouts. Since DIM works to balance estrogen receptors, it can help clear up adult hormonal acne in women.Ĭlick here to shop for DIM supplements. Estrogen imbalance, in particular, is a common cause of acne. Hormonal modulation can occur via prescriptions (such as birth control pills) or natural supplementation. With that in mind, most d ermatologists agree that the best way to clear hormonal acne i s to combine effective topical treatment with hormonal modulation. The root cause of hormonal acne is an imbalance of estrogen, progesterone, and testosterone, which affects the skin's oil-producing glands. DIM is believed to help with estrogen balance by increasing beneficial 2-hydroxy estrogens and reducing the unwanted 16-hydroxy variety. It is believed that DIM may help balance hormones by blocking the effects of excess testosterone, an androgen (male) hormone responsible for producing excess acne-causing sebum (oil) in the skin. What does DIM do?Įxtensive research shows that DIM can have a balancing effect on hormones and helps restore estrogen balance. Some dermatologists believe it might work similarly to spironolactone, a drug often recommend to treat hormonal acne. A few studies have found a correlation between a diet rich in cruciferous vegetables and a reduced risk for certain cancers, including breast and prostate cancer.
When you eat these superfoods, your stomach acid breaks down indole-3-carbinol to produce a new DIM compound. This botanical family includes cruciferous vegetables such as cabbage, Brussel sprouts, broccoli, and cauliflower. What is DIM?ĭIM is the main biologically active compound in a group of plants called cruciferous vegetables or Brassica. That's where Diindolylmethane (DIM) comes in. Most dermatologists agree that combining effective topical treatment with hormonal modulation is the best way to clear up hormonal acne breakouts. This imbalance leads to overactivity in the oil production glands. This type of acne occurs when the body's hormones ( estrogen, progesterone, and testosterone) are out of balance. A study published in the Journal of the American Academy of Dermatology showed that 50% of women in their twenties, 35% in their thirties, and 26% in their forties suffer from hormonal and adult acne. Anyone suffering from hormonal acne knows that it can be particularly challenging to treat.
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